欧盟评估扩展使用转基因黑曲霉菌株NZYM-BF生产的葡聚糖1，4-α-葡萄糖苷酶的安全性

核心提示：2026年5月8日，欧盟食品安全局就一种食品酶葡聚糖1，4-α-葡萄糖苷酶（glucan-1,4-α-glucosidase）的安全性评价发布意见。……（世界食品网-www.shijieshipin.com）

　　 2026年5月8日，欧盟食品安全局就一种食品酶葡聚糖1，4-α-葡萄糖苷酶（glucan-1,4-α-glucosidase）的安全性评价发布意见。
　　据了解，这种食品酶是由转基因黑曲霉菌株NZYM-BF生产的，旨在用于3种食品生产过程。

　　经过评估，专家小组得出结论，这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下：

　　The food enzyme glucan 1,4-α-glucosidase (4-α-d-glucan glucohydrolase; EC 3.2.1.3) is produced with the genetically modified Aspergillus niger strain NZYM-BF by Novozymes A/S. The safety of this food enzyme was evaluated previously and it did not give rise to safety concerns when used in two food manufacturing processes. Subsequently, the applicant has requested to extend its use to include one additional process. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of three food manufacturing processes. As the food enzyme–Total Organic Solids (TOS) are removed from the final foods in one process, the dietary exposure to the food enzyme–TOS was estimated for the remaining two food manufacturing processes. It was calculated to be up to 4.431 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1306 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 307. based on the new data, the revised margin of exposure and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.