欧盟评估转基因里氏木霉菌株DP-Nyn90生产的葡聚糖1，4-α-麦芽水解酶的安全性

核心提示：2025年10月16日，欧盟食品安全局就一种食品酶葡聚糖1，4-α-麦芽水解酶（glucan 1,4-α-maltohydrolas）的安全性评价发布意见。……（世界食品网-www.shijieshipin.com）

　　 2025年10月16日，欧盟食品安全局就一种食品酶葡聚糖1，4-α-麦芽水解酶（glucan 1,4-α-maltohydrolas）的安全性评价发布意见。
　　据了解，这种食品酶是由转基因里氏木霉菌株DP-Nyn90生产的，旨在用于加工谷物和其他谷物以生产蒸馏酒精。

　　经过评估，专家小组得出结论，这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下：

　　The food enzyme glucan 1,4-α-maltohydrolase (4-α-D-glucan α-maltohydrolase; EC 3.2.1.133) is produced with the genetically modified Trichoderma reesei strain DP-Nyn90 by Genencor International B.V. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in the processing of cereals and other grains for the production of distilled alcohol. Since residual amounts of food enzyme–total organic solids are removed during this food manufacturing process, dietary exposure was not calculated. A search for the homology of the amino acid sequence of the glucan 1,4-α-maltohydrolase to known allergens was made and matches with three respiratory allergens were found. However, when used for the production of distilled alcohols, the Panel considered that a risk of allergic reactions upon dietary exposure can be excluded. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.