云南
Product Profile
Product Name
ITGB4 (phospho Tyr1510) Antibody
Antibody Type
Primary Antibodies
Product description
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity ａnd motility.1) Suzuki S., EMBO J. 9:757-763(1990).
Immunogen
ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p)-S-T) derived from Human ITGB4 .
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity
MouseRat
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ITGB4
Alternative Names
GP150
ITB4
CD104 antigen
Molecular Weight(MW)
202 kDa
Tissue Specificity
The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510.
Database Links
Entrez Gene
3691
Protein Accession
NP_000204.3
Application
Application
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).
Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Additional Information
Form
Liquid
Storage Instructions
Store antibody at -20˚C for up to one year.
Storage Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.
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