云南
Product Profile
Product Name
Anti-TGF beta1 antibody
Antibody Type
Primary Antibodies
Immunogen
Polypeptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHCWB
WB:1:200-1:2000
IHC:1:200-1:1000
Species Reactivity
GoatHumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
TGFB1
Gene Synonyms
More
CED
LAP
DPD1
TGFB
IBDIMDE
TGFbeta
TGF-beta1
Gene Full Name
transforming growth factor beta 1
Gene Summary
More
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment ａnd activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) ａnd a mature peptide, ａnd is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, ａnd a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation ａnd growth, ａnd can modulate expression ａnd activation of other growth factors including interferon gamma ａnd tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, ａnd mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
Molecular Weight(MW)
44 kDa（Observed:53 kDa）
Cellular Localization
Extracellular region or secreted
Application
WB
- Western blot analysis using TGF beta1 antibody against Hela (1), A431 (2) cell lysate.
IHC
- Immunohistochemical analysis of paraffin-em
- bedded lung cancer tissues using TGF beta1 antibody with DAB staining
Application Notes
WB:1:200-1:2000
IHC:1:200-1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle
Storage Buffer
Purified antibody in PBS with 0.05% sodium azide
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