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一 、论文信息
2020年1月10日广元市中心医院联合兰州市口腔医院、四川大学口腔疾病研究国家重点实验室、兰州大学口腔医学院在OncoTargets and Therapy期刊上发表的题为“Icariin Mitigates the Growth and Invasion Ability of Human Oral Squamous Cell Carcinoma via Inhibiting Toll-Like Receptor 4 and Phosphorylation of NF-κB P65”(淫羊藿苷通过抑制toll样受体4和NF-κB P65磷酸化抑制人口腔鳞状细胞癌的生长和侵袭能力)的论文。
图片来源:PubMend
作者信息:
1、广元市中心医院口腔科:Ke Lei,Tan Ling,Lunchang Wang
2、广元市中心医院呼吸科:Bing Ma,Ping Shi
3、兰州市口腔医院牙髓科:Che Jin
4、四川大学口腔疾病研究国家重点实验室:Longjiang Li
5、兰州大学口腔医学院口腔修复科:Xiangyi He
二 、论文质疑
质疑一
[右上]图5B与[左]图6D、[中上]图4C、[右下]图6C图框中疑似重复。
[左]图6D来自论文"MiR-181c-5p Mitigates Tumorigenesis in Cervical Squamous Cell Carcinoma via Targeting Glycogen Synthase Kinase 3β Interaction Protein (GSKIP)" (Li 等人2020).
https://pubmed.ncbi.nlm.nih.gov/32547080/
[中上]图4C来自论文"MiR-320d suppresses the progression of breast cancer via lncRNA HNF1A-AS1 regulation and SOX4 inhibition" (Shi等人2018) [已撤回].
https://pubmed.ncbi.nlm.nih.gov/36275161/
[右下]图6C来自论文"Astragaloside IV (AS-IV) alleviates the malignant biological behavior of hepatocellular carcinoma via Wnt/b-catenin signaling pathway" (Jiang & Mao 2019).
https://pubmed.ncbi.nlm.nih.gov/35528074/
(康百拓多倍镜查重)
质疑二
从左上角顺时针方向:
图2A.与图3H,I、图2A、图1C、图4B、图1B相同颜色图框疑似重复。
图3H,I来自论文"The Down-Regulation of TrkB Alleviates the Malignant Biological Behavior and Cancer Stem-Like Property of Laryngeal Cancer" (Hu等人2020).
https://pubmed.ncbi.nlm.nih.gov/32801910/
图2A来自论文"Puerarin 6″-O-xyloside suppressed HCC via regulating proliferation, stemness, and apoptosis with inhibited PI3K/AKT/ mTOR" (Li等人2020).
https://pubmed.ncbi.nlm.nih.gov/32691991/
图1C来自论文"Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway" (Zhou等人2020).
https://pubmed.ncbi.nlm.nih.gov/31820522/
图4B来自论文"Ligustrazine inhibits the viability and motility of colon cancer cells" (Chen等人2020).
https://pubmed.ncbi.nlm.nih.gov/35117686/
图1B来自论文"The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition in vitro and oncogenesis in nude mice" (Wang 等人2020).
https://pubmed.ncbi.nlm.nih.gov/32566617/
(康百拓多倍镜查重)
同时与下述论文中图片疑似重复,从左上角顺时针方向:
图1D,E来自论文"Ganoderan (GDN) Regulates The Growth, Motility And Apoptosis Of Non-Small Cell Lung Cancer Cells Through ERK Signaling Pathway In Vitro And In Vivo" (Wang等人2019).
https://pubmed.ncbi.nlm.nih.gov/31695437/
图4C来自论文"The anti-tumor effect of taxifolin on lung cancer via suppressing stemness and epithelial-mesenchymal transition in vitro and oncogenesis in nude mice" (Wang 等人2020).
https://pubmed.ncbi.nlm.nih.gov/32566617/
图2A来自论文"Vitexin attenuates epithelial ovarian cancer cell viability and motility in vitro and carcinogenesis in vivo via p38 and ERK1/2 pathways related VEGFA" (Zhou等人2020).
https://pubmed.ncbi.nlm.nih.gov/33240988/
图1C来自论文"Wogonoside Attenuates Cutaneous Squamous Cell Carcinoma by Reducing Epithelial– Mesenchymal Transition/Invasion and Cancer Stem-Like Cell Property" (Wang等人2020).
https://pubmed.ncbi.nlm.nih.gov/33116592/
图1C来自论文"Tanshinone I attenuates the malignant biological properties of ovarian cancer by inducing apoptosis and autophagy via the inactivation of PI3K/AKT/mTOR pathway" (Zhou等人2020)
https://pubmed.ncbi.nlm.nih.gov/31820522/
图1A来自论文"Lung cancer A549 cells suppressed with overexpressed HNF1B or PCDHA13 inhibited PI3K/AKT phosphorylation" (Kang等人2020).
https://pubmed.ncbi.nlm.nih.gov/35117749/
(康百拓多倍镜查重)
三 、作者回复
针对质疑,暂未收到作者任何回复。
四 、期刊回复
暂未收到期刊任何回复。
参考信息:
https://pubpeer.com/publications/538546F89999005301C3380ECBBD30#4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971293/
https://pubmed.ncbi.nlm.nih.gov/32547080/
https://pubmed.ncbi.nlm.nih.gov/36275161/
https://pubmed.ncbi.nlm.nih.gov/35528074/
https://pubmed.ncbi.nlm.nih.gov/32801910/
https://pubmed.ncbi.nlm.nih.gov/32691991/
https://pubmed.ncbi.nlm.nih.gov/31820522/
https://pubmed.ncbi.nlm.nih.gov/35117686/
https://pubmed.ncbi.nlm.nih.gov/32566617/
https://pubmed.ncbi.nlm.nih.gov/31695437/
https://pubmed.ncbi.nlm.nih.gov/33240988/
https://pubmed.ncbi.nlm.nih.gov/33116592/
https://pubmed.ncbi.nlm.nih.gov/31820522/
https://pubmed.ncbi.nlm.nih.gov/35117749/
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