2025 ESMO | 精彩抢先看！结直肠癌领域中国研究一览

一年一度的肿瘤领域盛会——2025年欧洲肿瘤内科学会年会（ESMO 2025）将于10月17日至21日在德国柏林隆重举行，届时将揭示众多前沿临床科研成果，并吸引全球知名专家教授进行研讨，共同促进临床肿瘤学的发展与进步。

目前，官网披露了本次大会的入选摘要标题，在结直肠癌的Poster和e-Poster领域，中国专家共有40项研究入选。医脉通特此整理如下，让我们先睹为快！

Poster session

1

摘要号：733P

研究名称（英文）：Efficacy and safety of atezolizumab (Atezo) with or without tiragolumab (Tira) following neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (NEOTERIC): a multicenter, randomized, open-label, parallel-group phase II study

讲者：许剑民 | 复旦大学附属中山医院

2

摘要号：739P

研究名称（英文）：Deepath-MSI: A Clinic-Ready Deep Learning Model for Microsatellite Instability Detection in Colorectal Cancer Using Whole-Slide Imaging

讲者：Feng Xu | 中国上海

3

摘要号：741P

研究名称（英文）：Chemoradiotherapy (CRT) followed by sequential tislelizumab (TIS) + CAPOX and TIS for organ preservation in low rectal cancer (RELIEVE-01): primary results

讲者：汤文涛 | 复旦大学附属中山医院

4

摘要号：749P

研究名称（英文）：A multicenter, randomized, phase II trial of short-course radiotherapy or long-course chemoradiation followed by mFOLFOXIRI consolidation chemotherapy for organ preservation in low rectal cancer

讲者：Kai Han | 中国广州

5

摘要号：750P

研究名称（英文）：The Clinical Utility of Dynamic ctDNA in Predicting Response to Neoadjuvant Chemotherapy in Locally Advanced Rectal Cancer: A Post Hoc Analysis of the CONVERT Trial

讲者：Jing-Hua Tang | 中国广州

6

摘要号：753P

研究名称（英文）：Global Burden of Colorectal Cancer from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 and Projections to 2035

讲者：Liwei Fan | 中国北京

7

摘要号：756P

研究名称（英文）：Machine Learning-Driven Integration of Gut Mucosal and Circulating Microbial Biomarkers for Superior Early Diagnosis of Colorectal Cancer

讲者：Ning Zhao | 中国西安

8

摘要号：762P

研究名称（英文）：Confounders for incident colorectal cancer associated with smoking differ by sex

讲者：Hong-Hong Zhu | 中国衢州

9

摘要号：763P

研究名称（英文）：Clinical validation of the blood-based multiplex methylation assay, ColonAiQ, as a diagnostic aid for early detection of colorectal cancer

讲者：Xiaoyan Zhou | 中国上海

10

摘要号：765P

研究名称（英文）：Interim analysis of Protector-C study：a prospective, multicenter cohort of utilizing circulating tumor DNA (ctDNA) methylation as postoperative surveillance for colorectal cancer (CRC)

讲者：王锡山 | 中国医学科学院肿瘤医院

11

摘要号：773P

研究名称（英文）：Integration of Cadonilimab into Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer: Phase II Efficacy and Safety Outcomes

讲者：Lingling Feng | 中国深圳

12

摘要号：778P

研究名称（英文）：Prognostic Significance of Tumor Deposits in Locally Advanced Rectal Cancer: Post-hoc Analysis of a Phase III Trial

讲者：RunKai Cai | 中国广州

13

摘要号：779P

研究名称（英文）：Preoperative Short-course Radiotherapy followed by Chemotherapy and PD-L1 inhibitor for Locally Advanced Rectal Cancer: a prospective phase II study

讲者：Ting Wang | 中国郑州

14

摘要号：783P

研究名称（英文）：Neoadjuvant envafolimab combined with chemoradiotherapy in locally advanced rectal cancer: an exploratory, phase II study

讲者：Xu Guan | 中国北京

15

摘要号：784P

研究名称（英文）：Extracellular volume fraction and standardized iodine concentration of dual-energy CT for prediction of metastatic lymph nodes in rectal cancer

讲者：Menghong Zou | 中国绵阳

16

摘要号：786P

研究名称（英文）：Serplulimab Combined with CapeOX and Celecoxib as Neoadjuvant Therapy for Proficient Mismatch Repair Locally Advanced Mid-to-Low Rectal Cancer (SCAR)

讲者：丁克峰 | 浙江大学医学院附属第二医院

17

摘要号：796P

研究名称（英文）：A phase II trial to evaluate the safety and efficacy of SSGJ-707, a bispecific antibody targeting PD-1 and VEGF, in combination with chemotherapy in patients with metastatic CRC

讲者：徐晓晶 | 上海交通大学医学院附属仁济医院

18

摘要号：797P

研究名称（英文）：Irinotecan Liposome combined with 5-FU/LV and Bevacizumab as Second-Line Therapy for Metastatic Colorectal Cancer (IRIS): A Prospective, Multicenter, Single-Arm Phase II Study

讲者：Guingying Wang | 中国石家庄

19

摘要号：800P

研究名称（英文）：A multicenter randomized phase II trial assessing the efficacy and safety mCapOX plus cetuximab with mFOLFOX6 plus cetuximab as first-line treatment for patients with RAS/BRAF wild-type metastatic colorectal cancer: Updated results of the CAPCET study

讲者：周裕文 | 四川大学华西医院

20

摘要号：806P

研究名称（英文）：Efficacy and safety of JSKN003, a biparatopic anti-HER2 antibody conjugate (ADC), in patients with HER2-positive metastatic colorectal cancer (mCRC)

讲者：Dan Liu | 中国北京

21

摘要号：807P

研究名称（英文）：Efficacy and Safety of HBM4003, an anti-CTLA-4 Antibody, Combined with Tislelizumab in MSS Metastatic Colorectal Cancer: A Multicenter, Phase II Study

讲者：张盼盼 | 北京大学肿瘤医院

22

摘要号：815P

研究名称（英文）：Prospective Evaluation of Deepath-MSI for Microsatellite Instability Assessment in Colorectal Cancer: A Novel Whole Slide Image-Based Approach Versus Promega MSI Assay

讲者：Qian Wang | 中国上海

23

摘要号：819P

研究名称（英文）：AI-based blood test results predict origins for cancers of unknown primary

讲者：Fei Tian | 中国天津

24

摘要号：820P

研究名称（英文）：A Multicenter-Derived Nodal Classification System for Colon Cancer: Prognostic Significance of Metastatic Lymph Node Count and Anatomical Distribution

讲者：Zerong Cai | 中国广州

25

摘要号：831P

研究名称（英文）：Cadonilimab Combined with FOLFOXIRI and Bevacizumab as First-Line Treatment for Microsatellite Stable/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer (mCRC): Update Result from a Multicenter, Phase II Study (SYLT-026)

讲者：林榕波 | 福建省肿瘤医院

26

摘要号：836P

研究名称（英文）：Gut Microbiome and Metabolic Traits in Immunotherapy-Based Total Neoadjuvant Therapy for MSS Locally Advanced Rectal Cancer: A Longitudinal Cohort Study

讲者：Weiqing Lu | 中国上海

27

摘要号：842P

研究名称（英文）：Combining lines of therapy algorithms and large language models to detect progression of metastatic colorectal cancer patients in electronic health records

讲者：Yi-hsin Yang | 中国台南

28

摘要号：845P

研究名称（英文）：Liposomal irinotecan combined with capecitabine and bevacizumab as second-line therapy in metastatic colorectal cancer: A multi-center, single-arm study

讲者：Dan Su | 中国哈尔滨

29

摘要号：854P

研究名称（英文）：Effect of immunonutrition on postoperative complications, nutrition and inflammatory status in patients with colorectal cancer: A prospective, observational study

讲者：周建平 | 中国医科大学附属第一医院

30

摘要号：860TiP

研究名称（英文）：Neoadjuvant short-course radiotherapy (SCRT) plus iparomlimab and tuvonralimab (QL1706), CAPOX, and regorafenib in locally advanced rectal cancer (LARC): A randomized, multicenter, non-comparative phase 2 trial in progress

讲者：丁培荣 | 中山大学肿瘤防治中心

e-Poster session

1

摘要号：863eP

研究名称（英文）：Impact of Inflammatory Status on Quality of Life in Patients with Advanced Colorectal Cancer: A Comprehensive Analysis

讲者：Xi Zhang | 中国北京

2

摘要号：866eP

研究名称（英文）：A phase II, open-label study of toripalimab, cetuximab plus FOLFIRI as first-line treatment of unresectable left-sided RAS/BRAF wild-type metastatic colorectal cancer (Tesla study)

讲者：朱梁军 | 江苏省肿瘤医院

3

摘要号：874eP

研究名称（英文）：First-line (1L) encorafenib + cetuximab + mFOLFOX6 in patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC) in China: results from the phase 3 BREAKWATER study

讲者：Xicheng Wang | 中国广州

4

摘要号：881eP

研究名称（英文）：Long-term neoadjuvant chemoradiotherapy (nCRT) combined with camrelizumab for locally advanced rectal cancer: a single-arm, prospective, phase II clinical study

讲者：Chung B. Zhao | 中国哈尔滨

5

摘要号：894eP

研究名称（英文）：Global Disease Burden of Colorectal Cancer Attributable to High BMI Has More Than Doubled Over the Past 30 Years

讲者：Wenjie W. Li | 中国佛山

6

摘要号：898eP

研究名称（英文）：Fruquintinib alternating with bevacizumab plus capecitabine as maintenance therapy after first-line treatment in metastatic colorectal cancer (mCRC): A multicenter, open-label, Phase II Study

讲者：廖旺军 | 南方医科大学南方医院

7

摘要号：905eTiP

研究名称（英文）：TORCH-iTNT: A randomized phase II trial of CAPOX plus PD-1 inhibitor with or without short-course radiotherapy for proficient mismatch repair locally advanced rectal cance

讲者：王雅琪 | 复旦大学附属肿瘤医院

8

摘要号：907eTiP

研究名称（英文）：FTM-JSNO-03:A phase II study of fecal microbiota transplantation (FMT) plus QL1706 plus Bevacizumab plus XELOX for first-line (1L) treatment of advanced Microsatellite-stable (MSS) type colon cancer with liver metastasis

讲者：Hanjue Dai | 中国常州

9

摘要号：911eTiP

研究名称（英文）：Node-sparing modified Short-Course Radiation Combined With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer : A randomized, prospective, multicenter, open-label clinical trial (mRCAT-C)

讲者：劳伟峰 | 浙江大学医学院附属邵逸夫医院

10

摘要号：912eTiP

研究名称（英文）：SCRT + mFOLFOX6 + PD-1 Antibody + Targeted Therapy for HIgh-Risk pMMR/MSS Rectal Cancer (CRIT)

讲者：Fang He | 中国广州

备注：排名不分先后

如有遗漏或任何问题，请给我们留言~

来源：ESMO官网

编辑：Babel

排版：Babel

执行：Aurora

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