云南
Product Profile
Product Name
eIF4B Antibody
Antibody Type
Primary Antibodies
Product description
More
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F ａnd EIF4-A. Binds near the 5＇-terminal cap of mRNA in presence of EIF-4F ａnd ATP. Promotes the ATPase activity ａnd the ATP-dependent RNA unwinding activity of both EIF4-A ａnd EIF4-F.1) Gingras, A. C. et al. (2001) Genes Dev. 15, 807-826. Duncan, R. ａnd Hershey, J. W. (1985) J. Biol. Chem. 260, 5493-5497. Duncan, R. F. ａnd Hershey, J. W. (1989) J. Cell Biol. 109, 1467-1481.
Immunogen
eIF4B (Ab-422) antibody was raised against a peptide sequence around aa.420~424 (T-G-S-E-S) derived from Human eIF4B.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCWB
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Species Reactivity
Human
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
EIF4B
Alternative Names
More
EIF-4B
PRO1843
PKB
RAC
Molecular Weight(MW)
80 kDa
Tissue Specificity
This antibody detects endogenous level of total eIF4B protein.
Database Links
Entrez Gene
1975
Protein Accession
NP_001408.2
Application
Application
- Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4B (Ab-422).
Application
- Western blot analysis of lysed extracts from 3T3 ａnd HL60 cells using eIF4B (Ab-422).
Application Notes
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100:
Additional Information
Form
Liquid
Storage Instructions
Store antibody at -20˚C for up to one year.
Storage Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.
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