Product Profilea
Product Name
Glutamate receptor 2 (Precursor) Antibody
Antibody Type
Primary Antibodies
Product description
More
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.1) Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34 (1): 53-67
Immunogen
Glutamate receptor 2 (Precursor) (Ab-880) antibody was raised against a peptide sequence around aa.878~882 (I-E-S-V-K) derived from Human Glutamate receptor 2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Western Blot: 1:500~1:1000:
Species Reactivity
HumanMouseRat
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
GRIA2
Alternative Names
More
GLUR2
GLURB
GluA2
HBGR2
GluR-K2
GRIA2
GluR-2
GluR-B
AMPA 2
Molecular Weight(MW)
100 kDa
Tissue Specificity
This antibody detects endogenous level of total Glutamate receptor 2 (Precursor) protein.
Database Links
Entrez Gene
2891
Protein Accession
NP_000817.2
Application
Application
- Western blot analysis of lysed extracts from mouse brain and rat brain tissue using Glutamate receptor 2 (Precursor) (Ab-880).
Application Notes
Western Blot: 1:500~1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store antibody at -20˚C for up to one year.
Storage Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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