云南
Product Profile
Product Name
TGF beta1 Antibody
Antibody Type
Primary Antibodies
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
4F9C10,1B11B7
Host Species
Mouse
Tested Applications
ICC/IFIHCWB
WB~~1:500 - 2000.:
Species Reactivity
Human
Concentration
1 mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
TGFB
Alternative Names
More
CED
DPD1
TGFB
TGFbeta
TGFB1
Molecular Weight(MW)
44341 Da
Function
More
Multifunctional protein that controls proliferation, differentiation ａnd other functions in many cell types. Many cells synthesize TGFB1 ａnd have specific receptors for it. It positively ａnd negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation ａnd differentiation in committed osteoblasts
Tissue Specificity
Highly expressed in bone. Abundantly expressed in articular cartilage ａnd chondrocytes ａnd is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage
Cellular Localization
Secreted, extracellular space, extracellular matrix
Database Links
Entrez Gene
7040
Nucleotide Accession
NP_000651.3
Application
Application
- Figure 1: Western blot analysis using anti-TGF beta1 monoclonal antiobdy against truncated TGF beta1 recombinant protein.
Application Notes
WB~~1:500 - 2000.:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified recombinant fragment of TGFbeta1 expressed in E. Coli.
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