属性
质量水平
100
检测方案
95% (HPLC)
形式
powder
反应适用性
reaction type: Coupling Reactions
杂质
≤17wt. % water
应用
peptide synthesis
储存温度
−20°C
SMILES字符串
[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2
InChI
1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1
InChI key
BMTZEAOGFDXDAD-UHFFFAOYSA-M
相关类别
肽合成用氨基酸、树脂和试剂
应用
4-(4,6-二甲氧基-1,3,5-三嗪-2-基)-4-甲基吗啉盐酸盐可用作以下转化反应的缩合剂:
- 羧酸和胺在四氢呋喃中发生缩合反应,产生相应的酰胺。[1][2]
- 羧酸与醇的酯化反应,产生相应的酯。[3]
- 在质子溶剂中,将羧酸转化为相应的Weinreb酰胺。[4]
用作溶液和固相肽合成中的羧酸的活化剂;性能优于或相当于畅销的偶联剂[5][6]
Collagen-Based Fillers as Alternatives to Cyanoacrylate Glue for the Sealing of Large Corneal Perforations.
Chameen Samarawickramaet al.
Cornea, 37(5), 609-616 (2017-11-28)
To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations. A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These CLP-PEG hydrogels
Esterification of carboxylic acids with alcohols by 4-(4, 6-dimethoxy-1, 3, 5-triazin-2-yl)-4-methyl-morpholinium chloride (DMTMM).
Kunishima M
Synlett, 1999(08), 1255-1256 (1999)
Tetrahedron, 55, 13159-13159 (1999)
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