动物模型 / 心血管疾病模型 / 啮齿动物压力超负荷模型
压力超负荷模型
对啮齿动物横向主动脉结扎和腹主动脉结扎可引起的左心室肥大和心力衰竭。
横向主动脉收缩小鼠模型和升主动脉带状大鼠模型是使用最广泛的压力超负荷模型。
压力超负荷模型对于研究肥大向心力衰竭的转化是非常有帮助的。
Trichrome-stained histological sections indicate increased fifibrosis in all disease groups compared with Sham, as well as greater
right-ventricular wall thinning in TAC-untreated animals compared with PVN OXT-treated animals(Jhansi Dyavanapalli et al.2020)
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