华南理工大学孙大文院士在国际食品最顶级期刊(TOP1)发表综述，阐述基于表面增强拉曼光谱技术在检测农产品中真菌毒素的最新研究进展

　　通信作者简介

　　孙大文 院士

　　孙大文（Da-Wen Sun）教授，华南理工大学现代食品工程研究中心主任，欧洲科学院（欧洲人文和自然科学院）（Academia Europaea）院士，爱尔兰皇家科学院（Royal Irish Academy）院士，波兰科学院（Polska Akademia Nauk）外籍院士，国际食品科学院（IAFoST）院士，国际农业与生物系统工程科学院（iAABE）院士，国际制冷科学院院士。主要研究方向食品质量安全快速检测、食品冷冻冷链和食品新型物理加工。2015年至2019年连续五年荣获科睿唯安（原汤森路透）“高被引科学家”称号（SCI H指数 = 102，SCOPUS H指数 = 106，Google Scholar H指数 = 120）。获2014年广东省科学技术奖一等奖，2016年教育部科技进步奖二等奖，2018年中国轻工业联合会科学技术进步奖一等奖，2018年广东省科技进步奖一等奖。

　　Fingerprinting and tagging detection of mycotoxins in agri-food products by surface-enhanced Raman spectroscopy: Principles and recent applications

　　Zhihui Wu, Hongbin Pu, Da-Wen Sun

　　Background

　　Mycotoxin contamination in agri-food products compromises human and animal health throughout the supply chains, thus the establishment of rapid and accurate methods for the detection of mycotoxins is essential for food safety assurance. Among the preferred spectral methods, surface-enhanced Raman scattering (SERS) has emerged as an attractive solution for detecting trace mycotoxins in complex food matrices due to its advantages of high sensitivity, rapidness and non-destructiveness. However, relevant developments in research in this field are scarcely reviewed.

　　Scope and approach

　　In the current review, the fundamentals of SERS and substrates for detecting mycotoxin in agri-foods are introduced, technical developments in the detection procedure including combined techniques, fingerprinting and SERS tagging and spectral optimizations such as using chemometrics are elaborated. Recent applications of SERS methods for trace level detection of mycotoxins in agri-food samples including cereal grains, fruits, dairy products, and wine are also highlighted, and limitations and future prospects for developing the SERS technology for detecting mycotoxin contamination are finally presented.

　　Key findings and conclusions

　　SERS is a rapid and sensitive technique for detecting trace mycotoxins. However, the preparation of high-performance SERS substrates for on-site quantitative analysis of real food samples is still a challenging scientific problem. Future research should focus on designing reliable SERS substrates, establishing SERS fingerprint libraries of mycotoxins, and developing accurate chemometric methods, and choosing suitable combined techniques in order to achieve an early adoption of the SERS method as a practical tool for detecting mycotoxin contamination in the agri-food industry.

　　该文章《Fingerprinting and tagging detection of mycotoxins in agri-food products by surface-enhanced Raman spectroscopy: Principles and recent applications》于《Trends in Food Science & Technology》2021年2月15日在线出版。点击下方阅读原文即可查看摘要原文。

　　编辑：袁艺；责编：张睿梅