湖北
乙胺嘧啶 58-14-0
产品信息
中文名
乙胺嘧啶
中文同义
6-乙基-5-(4-氯苯基)-2,4-嘧啶二胺;2,4-二氨基-6-乙基-5-对氯苯基嘧啶;比利美胺;达拉匹林;乙胺嘧啶;息疟定;乙嘧啶,息疟定;马来酰亚胺-羧酸
英文名
Pyrimethamine
英文同义
2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine;[2-amino-5-(4-chlorophenyl)-6-ethyl-pyrimidin-4-yl]amine;Pyrimethamine,5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine;Pyrimethamine (200 mg);PyriMethaMine,darapriM;5-(p-chlorophenyl)-6-ethyl-4-pyrimidinediamine;BW 50-63;bw50-63
CAS
58-14-0
分子式
C12H13ClN4
分子量
EINECS
200-364-2
相关类别
有机化工原料;医药兽药;原料;兽药原料药;医用原料;分析标准品;医药中间体;其他兽药标准品;中间体;医药原料;小分子抑制剂;APIs & Intermediate;Pyrimidine;Amines;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Inhibitor;Heterocycle-Pyrimidine series;DARAPRIM;其他科研原料药;法医和兽医标准品;嘧啶;化合物：原料药;原料药;医用原料;日用化学品原料;药物杂质及中间体;医药原料药;原料;医药、农药及染料中间体;Organics
结构式
性质
熔点
233-234°C
沸点
393.35°C (rough estimate)
密度
1.2171 (rough estimate)
折射率
1.6110 (estimate)
储存条件
0-6°C
溶解度
Prepare the solution immediately before use. Dissolve 0.25 g in a mixture of 1 volume of methanol R and 3 volumes of methylene chloride R and dilute to 10 mL with the same mixture of solvents. The solution is clear (2.2.1) and not more intensely coloured than reference solution BY6 (2.2.2, Method II).
酸度系数(pKa)
pKa 7(t=20.0) (Uncertain)
形态
neat
水溶解性
<0.01 g/100 mL at 21 ºC
最大波长(λmax)
276nm(lit.)
Merck
14,7985
BRN
稳定性
Stable, but light sensitive. Combustible. Incompatible with strong oxidizing agents.
NIST化学物质信息
Pyrimethamine(58-14-0)
(IARC)致癌物分类
3 (Vol. 13, Sup 7) 1987
EPA化学物质信息
Pyrimethamine (58-14-0)
category：精细化学|
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