北京
核心提示：2026年10月8日，欧盟食品安全局就一种食品酶环糊精葡萄糖基转移酶（cyclomaltodextrin glucanotransferase）的安全性评价发布意见。……（世界食品网-www.shijieshipin.com）
2026年10月8日，欧盟食品安全局就一种食品酶环糊精葡萄糖基转移酶（cyclomaltodextrin glucanotransferase）的安全性评价发布意见。
据了解，这种食品酶是由转基因大肠杆菌K-12菌株DSM 34230生产的，旨在用于生产特殊碳水化合物(γ-环糊精)的糖加工。
经过评估，专家小组认为，在预期的使用条件下，不能排除通过饮食接触引起过敏反应的风险，但这种情况发生的可能性很低。根据所提供的数据，小组得出结论，该食品酶在预期的使用条件下不会引起安全问题。部分原文报道如下：
The food enzyme cyclomaltodextrin glucanotransferase (1,4-α-d-glucan 4-α-d-[1,4α-d-glucano]-transferase (cyclising); EC 2.4.1.19) is produced with the genetically modified strain Escherichia coli K12 DSM 34230 by Wacker Chemie AG. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism, but not from recombinant DNA. It is intended to be used in the processing of sugars for the production of specialty carbohydrates (γ-cyclodextrins). Since residual amounts of food enzyme–total organic solids are removed during the production of γ-cyclodextrins, dietary exposure was not calculated and toxicological testing was not needed. A search for the homology of the amino acid sequence of the cyclomaltodextrin glucanotransferase to known allergens was made and matches with two respiratory allergens were found. The Panel considered that a risk of allergic reactions upon dietary exposure cannot be excluded, but that the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
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