第二轮会议预告 | SMART Symposium靶向蛋白降解：从基础研究到临床应用

靶向蛋白降解（TPD）是一项革命性技术，它能够利用包括泛素-蛋白酶体和溶酶体途径在内的天然细胞过程，选择性地消除特定的相关蛋白质。TPD技术在治疗癌症、神经退行性疾病、自身免疫性疾病、炎症、病毒和细菌感染等各种疾病方面前景广阔。鉴于 TPD 有潜力克服小分子药物和生物制剂等传统药物模式所面临的挑战，它已赢得了全球学术界、制药业和投资者的极大关注。

Targeted protein degradation (TPD) stands as a revolutionary technology capable of selectively eliminating specific proteins of interest by leveraging natural cellular processes, including the ubiquitin-proteasome and lysosome pathways. TPD technology holds immense promise for the treatment of diverse diseases, ranging from cancer, neurodegenerative diseases, autoimmune disorders, inflammatory ailments, to viral and bacterial infections. Given its potential to overcome the challenges associated with traditional drug modalities like small molecules and biologics, TPD has garnered significant attention from academia, pharmaceutical industry, and investors world-wide.

本次研讨会的主题将围绕通过化学和生物创新开发和应用TPD技术展开，该技术不仅可以作为一种研究工具来探究和发现新的生物学特性，还可以作为一种治疗方法来治疗人类疾病。欢迎加入这场将在中国深圳举办的激动人心的研讨会，我们将与来自世界各地具有不同背景的同行们一起进行热烈的讨论和交流，并共同探索精彩的演讲和海报展示。

The theme of this symposium will be centered on development and application of TPD through chemical and biological innovations, serving not only as a research tool to interrogate and uncover new biology but also as a therapeutic modality to treat human diseases. Join us in lively discussion, networking opportunities with colleagues from diverse backgrounds worldwide, and to discover inspiring presentations and poster sessions at this exciting gathering in Shenzhen, China.

会议信息

CONFERENCE INFORMATION

会议时间：2024年11月12日-14日

Date: November 12-14, 2024

会议地点: 广东省深圳市光明区天安云谷国际会议中心

Venue: Cloud Park International Conference Center, Guangming District, Shenzhen, Guangdong, China

报名截止时间：2024年11月9日

Deadline for Registration: November 9, 2024

海报规格：宽 80cm × 高 120cm

Poster Size：Width 80cm × Height 120cm

参会方式：线下

Participation: In-person

会议语言：英语（无同声传译）

Language: English (No simultaneous interpretation)

会议主题

CONFERENCE THEME

蛋白水解靶向嵌合体 (PROTAC)

Proteolysis targeting chimera (PROTAC)

分子胶和诱导接近

Molecular glue and induced proximity

靶向蛋白降解 (TPD)在药物研发中的应用

Targeted protein degradation (TPD) in drug discovery and development

膜蛋白降解（MPD）

Membrane protein degradation (MPD)

结构生物学、蛋白质组学和新技术

Structural biology, proteomics, and new modalities

会议组委会

ORGANIZING COMMITTEE

颜宁 Nieng Yan

深圳医学科学院 Shenzhen Medical Academy of Research and Translation

深圳湾实验室 Shenzhen Bay Laboratory

清华大学 Tsinghua University

Nathanael Gray

斯坦福大学 Stanford University

Alessio Ciulli

邓迪大学 University of Dundee

陈鹏 Peng Chen

北京大学 Peking University

深圳湾实验室 Shenzhen Bay Laboratory

颜士翔 Frank Yan

本草资本 3E Bioventures

会议日程

CONFERENCE PROGRAM

报告人

INVITED SPEAKERS

会议注册

REGISTRATION

1. 请于2024年11月9日前通过网站填写注册信息 （长按二维码进入会议网站） 。

1. Please fill in your registration information before November 9, 2024 via the website: https://symposia.smart.org.cn

扫码报名 Scan to Register

2. 会议注册费：注册费包含11月12日至14日的午餐，以及11月13日的晚餐。

2. Registration Fee: The registration fee includes lunch on Nov. 12 through 14, and dinner on Nov. 13.

如您是学生，请上传有效证件供工作人员审核。

Please upload valid documents for review if you are a student.

注册类别
Register Type
国内支付
Domestic Payment
国际支付
International Payment
学生
Student ¥1600 $220
学术
Academic ¥2600 $360 企业
Corporate ¥3600 $500

注意 Notice

1. 会议不设现场报名，请于2024年11月9日前完成报名与缴费。

1. The conference does not accept on-site registration. Please complete the registration and payment before November 9, 2024.

2.转账时请备注：TPD+您的姓名

2.When making the transfer, please include the following note: TPD+your name.

3. 注册费电子发票将于会后15个工作日内发送至注册邮箱。

3. The electronic invoice for the registration fee will be sent to the registered email address within 15 working days after the symposium.

4.11月11日18:00后取消参会将无法申请退款。

4.Refunds will not be available after 18:00 on November 11.

墙报环节

POSTER SESSION

本次会议设有墙报展示环节，并设优秀墙报奖。我们诚邀您提交题目，参与墙报展示会 （鼓励展示最新研究进展或未发表的研究课题） 。

This conference will feature a poster presentation session, with an award for outstanding posters. We sincerely invite you to submit your topics and participate in the poster presentation (latest research advancements or unpublished research topics are encouraged) .

参与方式：在注册网址中上传墙报信息

How to participate:Upload poster information to the registration website.

墙报要求：若您参与墙报展示，请自行打印并携带至会议现场，交由工作人员在指定位置张贴。

Poster requirements:If you participate in the poster presentation,please print the poster yourself and bring it to the conference venueto be posted in the designated area by the staff.

墙报规格：宽 80cm × 高 120cm

Poster size:Width 80cm × Height 120cm

墙报申请截止日期：2024年11月9日

Deadline:November 9, 2024

会议住宿

ACCOMMODATION

本次会议不统一安排住宿，参会代表可自行联系附近酒店。

We do not provide centralized accommodation for this conference. Participants can arrange their own accommodation by contacting nearby hotels.

深圳光明天安云谷逸衡酒店

EVEN Hotels Shenzhen Guangming Cloud Park, an IHG Hotel

地址：深圳市光明区新湖街道圳美社区圳园路98号（距离会场步行200米，步行3分钟）

Address: No.98 Zhenyuan Road, Zhenmei Community, Xinhu Street, Guangming District, Shenzhen. (The hotel is 200 metres from the conference venue, which takes 3 mins by foot.)

深圳光明天安云谷智选假日酒店

Holiday Inn Express Shenzhen Guangming Cloud Park, an IHG Hotel

地址：深圳市光明区圳美大道68号（距离会场步行200米，步行3分钟）

Address: No.68 Zhenmei Road, Guangming District, Shenzhen. ( The hotel is 200 metres from the conference venue, which takes 3 mins by foot. )

深圳光明中集行政公寓酒店

Guangming CIMC Executive Apartments Hotel

地址：深圳市光明区凤凰街道侨明路中集行政公寓酒店（距离会场7.6公里，驾车22分钟）

Address: CIMC Executive Apartments Hotel, Qiaoming Road, Fenghuang Street, Guangming District, Shenzhen. (The hotel is 7.6 kilometers from the conference venue, which takes 22 mins by car.)

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复制链接到浏览器进入会议网站：https://symposia.smart.org.cn/sym/event/02c7c44a1a4e44039e9dab4b4ccb3ad6/4be7101e-c25a-4377-b5e8-b3b4eeaf0df4